hrp0097p2-155 | Adrenals and HPA Axis | ESPE2023

A case of Ectopic ACTH in a girl with thymic carcinoid

Deodati Annalisa , Bizzarri Carla , Ubertini Graziamaria , Carmen Garganese Maria , Stigliano Antonio , Cappa Marco

Background: Ectopic ACTH-producing tumors rarely occur in children, with <1% of all adolescents with Cushing Syndrome (CS). Many cases of ACTH-secreting ectopic neuroendocrine tumors (NETs) are reported in literature. In most patients, tumors secrete corticotropin-like peptides and/or corticotropin releasing factor (CRF)-like peptide, which stimulate cortisol hyperproduction.Background: Ectopic ACTH-producing tumors r...